01:377:370 Lecture Notes - Lecture 37: Diabetes Mellitus Type 2, Lipoprotein Lipase, Glucose Transporter
29 Apr 2019
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Secreted from interstitial cells of testes; masculinizing effects. Sex hormone binding globulin transports testosterone to target tissue, where it then migrates to cell nucleus. Major effect for exercise: anabolic and strength. May also promote gh release and initiate structural protein changes; interacts with neurons- stronger contractions. Plasma concentration increases during prolonged submax work, maximal exercise, and during some strength training workouts (heavy resistance, short intervals, large muscle) Regulate ovulation and menstruation; disturbance due to excessive exercise can lead to amenorrhea; estrogen may enhance lipoprotein lipase activity. Secreted from alpha cells in the islets of langerhans. Secreted from beta cells; stimulated by cho intake. Regulates entry of glucose into all tissues except the brain. Inulin activated a glucose transporter protein, glut4 in muscle; catecholamines suppress insulin. Lowers blood glucose but can enhance fat synthesis. Exercise is used at treatment for type ii diabetes. In general, the magnitude of hormonal response to a given exercise load declines with endurance training.
