11:680:390 Lecture Notes - Lecture 22: 2009 Flu Pandemic, Common Source, Common Cold

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22: Epidemiology
I. Epidemiology - the study of the occurrence, distribution, and determinants of health and
disease in a population; identifying the nature of a disease and its transmission
A. Epidemiologists
1. Rely on surveillance → observation, recognition, reporting of diseases
2. Can trace the spread of disease to identify its origin and mode of
transmission
B. Disease and Prevalence
1. Incidence: number of new cases
of the diseases in a given period of time
2. Prevalence: total number of new and existing cases
in a population in a
given time
3. Why don’t we have the flu in the summer? Not in classrooms, more
open windows, people are outside more
C. The Scope of Disease
1. A disease outbreak occurs when a number of cases of a disease are
reported in a short period of time
2. Carriers: diseased individuals who show no or mild symptoms have
subclinical infections
3. Types
Epidemic
Pandemic
Endemic
Sporadic
- a sudden, greater
occurrence over a longer
period of time (Ex. flu)
- across the world
(Ex. Zika, Influenza,
Swine Flu)
- a low number,
all the time (Ex.
common cold)
- occurring occasionally,
singly, or in scattered
instances (Ex. Ebola)
4. Outbreak - short burst
a) Common source - easier to stop; water or food
b) Host to host - harder to stop; animal to people (vice versa)
II. Stages of Disease
A. To cause a disease, a pathogen must replicate and grow inside a host
B. A well-adapted pathogen lives in balance with its host
1. Chronic infection: host and pathogen survive
C. New pathogens sometimes emerge for which the host has no resistance
1. Acute infections: pathogen can be a selective force
D. Stages
1. Infection
2. Incubation Period → environment held at
steady temperature; pathogen starts
replicating, gets used to the environment;
no symptoms; contagious
3. Acute Period → Symptoms start to
appear; contagious
4. Decline Period → Symptoms start to weaken
5. Convalescent Period → Recovery period
E. Mortality and Morbidity
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Document Summary

Epidemiology - the study of the occurrence, distribution, and determinants of health and disease in a population; identifying the nature of a disease and its transmission. 22: epidemiology: epidemiologists, rely on surveillance observation, recognition, reporting of diseases, can trace the spread of disease to identify its origin and mode of transmission, disease and prevalence. Incidence: number of new cases of the diseases in a given period of time. A sudden , greater occurrence over a longer period of time (ex. flu) A low number, all the time (ex. common cold) Occurring occasionally, singly, or in scattered instances (ex. Ebola: outbreak - short burst, common source - easier to stop; water or food, host to host - harder to stop; animal to people (vice versa) If high proportion of ind are immune to an infection, then the whole population will be protected.

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