33:630:363 Lecture Notes - Lecture 2: Sarcopenia, Malnutrition, Etiology

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Reduced appetite: decreased sense of taste or smell, isolation, increased inflammation due to disease. Declining functional status: decreased hearing and vision, decreased ability to shop/cook, impaired chewing, poor oral health, sarcopenia. Financial: limited access to grocery stores, food insecurity, increased medical costs. Impaired nutrient utilization: poor diet, food-medication interactions, decreased organ function. Adequate muscle mass: handgrip strength consistent with age, toned muscles, ct scan of muscles shows minimal fat infiltration. Sarcopenia: poor handgrip strength (< 16 kg/f, <27 kg/m, weak or flaccid muscles, ct scan shows infiltration of fat in muscles. Peak muscle mass achieved by age 25. 8% loss of lean soft mass per decade between 40-70 years. 15% loss of lsm per decade after age 70. Loss of 10% = impired immunity, increased risk for infection. Loss of 20% = decreased healing, weakness, infection. Loss of 30% = not able to sit up, increased risk for pressure injury, pneumonia.

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