33:630:363 Lecture Notes - Lecture 4: Iliac Crest, Bone, Bone Mineral
15 Jan 2020
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Document Summary
Trabecular bone 20: less dense, spongy appearance, most responsive to estrogen, locations: knobby ends of long bones, iliac crest, wrists, scapula, vertebrae. Cortical bone 80: compact, dense structure, shafts of long bones. Terms: osteoid: organic matrix of collagen, osteocyte: mature bone cell, osteoblasts: formation of bone tissue ( build up, osteoclasts: resorption of bone tissue ( claw down) Growth until mature height is achieved: females: age 16-18, males: 18-20. Bone consolidation occurs from mature height until age 30 peak bone mineral density. After bone growth is complete can lead to loss of bmd. Continuous bone resorption and bone reformation: most of adult skeleton is replaced every 10 years (both cortical and most trabecular, function of constant resorption/reformation, to repair damage to skeleton from stress, prevents accumulation of too much. Old bone: use of calcium and phosphorus stores. More resorption than formation in pre and post menopausal women; more formation in pubertal girls.
