BIOL 4376 Lecture Notes - Lecture 8: Benign Prostatic Hyperplasia, Shiga Toxin, Macconkey Agar

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21 Jun 2020
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Enterobacteriaceae/enterics largest group ubiquitous(commensal flora+incidental pathogens) rods facultative anaerobes (aerobes) all ferment glucose some ferment lactose ( Exotoxins: enterotoxin (food poisoning), cytotoxin, shiga toxin (shigella and strain 0157:h7 of e. coli) , rapid motility, hydroysis urea (less acidic) citrobacter: , nosocomial serratia (s. marcens): slow , nosocomial. Infections: biliary tract infection, abdominal infections(peritonitis, appendicitis, cholecystits), Bed sores(polymicrobial), wound infection(fecal contamination), neonatal meningitis: #3 cause, colonization of vagina, Prematurity, failure of protective igm antibodies to cross placenta, fecal contamination(delivery/amniotic fluid) e. coli associated. Diarrheal disease: 6 strains, various virulence factors, food borne (food- undercooked beef/unpasteurized, feces, fingers, flies), Campylobacter (c. jejune, c. coli, c. enteritis, c. fetus) curved rods (gull wing shape) primary cause of bacterial diarrhea motile- has 1 flagellum difficult do not form to culture spores (grows at 420c, does not ferment carbohydrates, requires co2 & o2) Fastidious = hard to culture food borne causes food poisoning is usually delf limiting in patients. & symptoms: malaise, fever, headache, diarrhae (can be bloody)

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