BIOL 221 Lecture Notes - Lecture 5: Axillary Lymph Nodes, Cervical Lymph Nodes, Dense Irregular Connective Tissue

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Lymphoid organs are larger and more organized than lymphoid tissues. Lymphoid organs include the lymph nodes, spleen and thymus. Function: filter debris, pathogens and other antigens from lymph. Lymph nodes filter the lymph, removing cellular debris and pathogens before the fluid is returned to the blood. Lymph nodes are located mainly where the appendages (inguinal and axillary lymph nodes) and head (cervical lymph nodes) join the trunk. the lymph nodes are important. Intestinal to drainage from gastrointestinal tract (especially the small intestine). Lymph nodes are small, ovoid structures surrounded by a capsule of dense irregular connective tissue. Trabeculae are extensions of the capsule that extend into the outer region, or cortex, that separates it into compartments. The outer cortex contains follicles with germinal centers where lymphocytes multiply. The medulla contains b cell lymphocytes, plasma cells and macrophages arranged as medullary cords. Spaces between the cords where lymph flows are called medullary sinuses.

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