BIOL 221 Lecture Notes - Lecture 6: Cytotoxic T Cell, Autoimmune Disease, Transplant Rejection
1 Mar 2020
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Document Summary
Organ transplant rejection: antigens on donor tissue attacked by recipient"s immune system, immunosuppressive therapy. Transplant rejection occurs when the recipient"s immune system reacts tissue. Corticosteriods suppress the donor"s to antigens on inflammation. Antilymphocyte globulins decrease the number of circulating lymphocyes. Immunosuppressant drugs cyclosporine costimulation required to activate cytotoxic t cells. like interfere with. Immunodeficiency: genetic / developmental errors, infections that destroy immune system, immunosuppression therapy. Immunodeficiencies may arise from genetic or developmental errors that cause a decrease in the ability to mount an immune response. They may also arise when infection destroys the immune system. the probability of. Immunosuppression transplant rejection also leads to immunodeficiency. therapy used to lessen. Genetic immunodeficiencies: severe combined immunodeficiency syndromes (scid, treated with gene therapy, bone marrow transplant, body, heal thyself (wheelwright, 2002) Severe combined immunodeficiency syndrome (scid) is an example of a genetic immunodeficiency. It can be treated with gene therapy or bone marrow transplant.
