BIO 121 Lecture Notes - Lecture 3: Nucleolus, Signal Peptide, Organelle
23 Nov 2020
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Document Summary
Double membrane surrounding the contents of the nucleus. Inner membrane of the nuclear envelope is underlain by the nuclear lamina. Mesh of filaments that support the nuclear envelope. Chromatin attaches to nuclear envelope via nuclear lamina. Telomeres + centromeres of the chromosomes are attached to the nuclear envelope (heterochromatin) During mitosis, nl plays a role in the breakdown of the nuclear envelope such that the chromosomes can be released and the mitotic spindle can form. Happens when nuclear lamins are phosphorylated cause destabilization of the nuclear lamina breakdown. Causes the nuclear envelope to also break apart. Once mitosis is over, the nuclear envelope is reformed after the phosphate group has left the lamins chroms+nuclear envelope attached to lamin everything is reformed. Ribonucleoproteins are made of both protein and rna (rrna) Ribosomal proteins are made in the cytosol and are imported to the nucleus and assembled with the rrna in the nucleolus.
