BIO 121 Lecture Notes - Lecture 17: Tunxis Community College, Vincristine, Cell Membrane
23 Nov 2020
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Document Summary
Dynein (-) end motor protein that moves towards the minus end of mt (towards. Kinesin (+) end motor proteins and moves towards the plus end of mt (away from centrosome: prevents er from collapsing in on nucleus. Map bind microtubules to neighboring microtubules network of mt growing the the same direction. Mt can be capped at the growing end by different maps at the plasma membrane (so. Mt don"t grow or shrink) influences cell shape (nerve cells/axons) Colchicine, colcemid binds tubulin dimers and prevents polymerization. Vinblastine, vincristine binds tubulin dimers and prevents polymerization. Highly concentrated in the cortex of cytoplasm (beneath plasma membrane) (though they are dispersed everywhere) Structure to pm, cell shape, crawling, cytokinesis, vesicle transport, streaming (plants) Allows change in morphology of cell + movement. More flexible than mt and found in bundles most dynamic of 3 cytoskeletal. Cc is different at both ends of filament (-) > (+) Actin bound with atp high affinity for g-actin.
