BSC 310 Lecture Notes - Lecture 13: Uracil, Heterocyst, Deoxyribose

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Carbon skeletons come almost exclusively from intermediates of glycolysis or the citric acid cycle (cid:1) Amino group is derived from inorganic n in the environment, usually ammonia (nh3), and incorporated by glutamate dehydrogenase or glutamine synthetase (cid:1) Amino group can be transferred from glutamate or glutamine to form other compounds (cid:1) (cid:1) (cid:1) (cid:1) Biochemistry behind purine and pyrimidine biosynthesis is complex. Both purines and pyrimidines are constructed from several carbon and nitrogen sources, including co2 (cid:1) Lipids are important structural components of membranes and serve as c and energy reserves. Archaea do not have fatty acids in their membrane lipids, instead use isoprene. Synthesized 2 c"s at a time using acyl carrier proteins (acp) The acp holds the growing fatty acid and releases it once it is finished. Each c2 unit incorporated originates from the c3 compound malonate (third c is released as co2) which is attached to the acp to form malonyl-acp.

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