BIO 200 Lecture Notes - Lecture 8: Frequency-Dependent Selection, Genetic Drift, Sickle-Cell Disease

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What outside forces can cause selection: predation is a strong selective force, climatic factors, parasitism, mate attraction, resource acquisition, more, absolute fitness: species with a stronger selective force have a higher fitness. (example: Black mice with 3 offspring have a fitness of 3, and white mice with 1 offspring have a fitness of 1: relative fitness: ratio of # of offspring out of highest possible of offspring (example: Fishermen selectively keep bigger fish: disruptive selection: against the average. Environmental shift two different phenotypes are both successful (example: agrostis tenuis grows in several areas with heavy contamination of metal in soil. Nearby grasses have uncontaminated soil does not have resistance. Uncontaminated soil has lower fitness. : balancing selection: actively maintained in the gene pool of a population at frequencies larger than expected from genetic drift alone. Heterozygote advantage (sickle cell anemia: higher fitness) Relative fitness: aa - . 75, aa 1 (heterozygote), aa - . 25.

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