BIO SCI 38 Lecture Notes - Lecture 1: Posttraumatic Stress Disorder, Basolateral Amygdala, Memory Consolidation
13 Jan 2020
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Lecture: glucocorticoids & norepinephrine work together to enhance memory consolidation. Glucocorticoids & norepinephrine work together to enhance memory consolidation. When it is injected systemically following inhibitory avoidance training, it enhances retention. However, the effect of dexamethazone also depends on epinephrine being released in the amygdala, because when injected into the amygdala, propranolol prevents dexamethazone from enhancing retention. Arousing events drive release of both norepinephrine and glucocorticoids, and they function in concert to influence memory. Glucocorticoids have two receptors: mineralicorticoid receptors (mr) and glucocorticoid receptors (gr) (1) it can initiate the acquisition and storage of the memory trace and. (2) it can activate the release of adrenal hormones that can. Modulatory systems make memories stronger by increasing the same cellular processes modulate the processes that store the memory. needed for ltp. Positive or negative experiences engage neuromodulatory systems (adrenal gland, locus coerulus, vta, basolateral amygdala, etc.
