ANFS251 Lecture Notes - Lecture 27: Pus, Antibiotics, Lymphadenopathy
Document Summary
Cytoplasmic membrane 1: a layer of phospholipids and proteins which encloses the interior of the bacterium, regulating the flow of materials in and out of the cell. Membranes are also dynamic, constantly adapting to different conditions: gram positive have one, gram negative have two. Serves as the attachment point of the cytoskeleton and the cell wall: the membranes contain a wide variety of proteins and lipids, governs the passage of molecules into and out of the cell, 100,000 glucose molecules/second. Involved in cell adhesion, cell signaling and ion channel conductance (ca++) Cytoplasmic membrane iii: the membrane is semi-permeable (it regulates what can enter the cell, movement of molecules can be either passive (no energy) or active (requires energy) Specific proteins (receptors) can act as molecular signals and transduce those signals into the cell. *gram negative bacteria have an outer membrane and an inner plasma membrane. Gram-negative bacteria have a large periplasmic space between the peptidoglycan layer and the plasma membrane.