BISC306 Lecture Notes - Lecture 15: Aldosterone, Exocytosis, Tryptophan

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Role of horizontal cells: the lateral pathway mediates the surround of a receptive field, horizontal cell flips the sign; so whatever happens to the cell on the right is opposite to what happens on the left. 2 fields of vision; one for each eye; these cross. Visual sensitivity exists in a large degree of illuminations. Hormones and the endocrine system: cell signaling: beyond the nervous system, communication with neighboring cells communication with distant cells, paracrine signaling and autocrine signaling, paracrine receptor on a different cell, autocrine receptor on the same cell, hormones. Many endocrine cells release hormone by exocytosis in a calcium dependent manner: neurons, neurosecretory cells, nonneural endocrine cells, local paracrine and autocrine signals. Steroid hormones are derived from cholesterol and are not stored but released upon synthesis: aldosterone, cortisol involved in glucose, testosterone (an androgen, estrogen (an androgen) Peptides and biogenic amines use gpcrs or enzyme/enzyme linked receptors: camp, enzyme/enzyme linked receptors cgmp, these are both metabotropic.

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