ANSC 452 Lecture Notes - Lecture 8: Lysosome, Perichondrium, Feedback
15 Nov 2020
School
Department
Course
Professor
Document Summary
4 in era nem branous ossification ectoderm ditterentiates into. 4 ender hon drae ossification apoptotic cartilage is replaced by este oblasts. 4 mesenchyme + chondrocyts schondrocytes die y osteoblasts replace l ostroblasts come from limb bonco or axial sites. 4 apoptosis releases lysosomal proteases odegrade cartilage) mitochondrial/ wy to plasmic ca initiate matriz calcification) Secondary sites of apoptosis are at the ends of bone that can still proliferate leads to long as proliferating zone of cartilage lepiphyseal plate more rapid expansion of bone. | rbc in blood vessels outside of bones & produces growth factors. Regulation of chondrocytes is done through hypertrophy /apoptosis. Pthip/ phpp paraply roid hormone related peptide made by chondrocytes, acts on proditerating chondrocytes, "^ chondrocyte pralift differentiation, wider growth plate & more long growish nie bigger. Indian hedgehog when ihh is expressed, they. Made by pre hypertrophic & hypertrophic condrocytes: no longer proliferate.
