ANSC 452 Lecture Notes - Lecture 1: Autocrine Signalling, Growth Factor
15 Nov 2020
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Document Summary
" mueti cellular organisms develop about 3 billion years than single-celled o rganisms because of the coordination cells produce growth factors that send messages to other receptors and effect other signaling. "hormones /growth factors are inter changable for this class. , peptides (<20) larger structures cannot easily enter cells. Endocrine delivery by circulation to distant targets. Contact juxta crine immobile ligand, usually on another cell. Neural stransported via azon to a distant target. Responses depend on effective on effective concentration receptor, & signaling. Effe the concentration benough for a cell to recognize something by pleiotropic o different effects depending on concentration. > receptor actlvity +present, correct location, able to function to intro cellular signaling some kind of cellular response results. Is changes ability to to bind to other proteins, use enzymes, etc. Polymerases, , trans ferases, isomerases other protein types. " proteins are polar, so they can dissolve inwater. Receptors can be on the membrane of the cell.
