ANSC 452 Lecture Notes - Lecture 14: Somatostatin, Mechanistic Target Of Rapamycin, Statin
10 Jan 2021
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Negative feedbacks high levels of hormone = releasing tactor reduced/ increased inhibitory factor y one of a hormone"s action inhibit itself. Growth hormone peptide hormone that stimulates growth. 4 somatotropin-> endogenous; somatropin. not made in the body to produced from pituitary gland. Lo hypothalamus produces ghrh ( g hrh binds to soma tropos) is stimulated by ghrelin, sex hormones deep sleep, fasting exercise hinnibited by somato statin in pituitary; thigh gh/igf-1, hyperglycemi? e cortiscal can stimulate somatostatin. Windirect effects igf production, a bone mineralization, a muscle mass. Direct effects to insulin sensitivity, & glucose use & proze in turnover, lipid metabolism growth effects are indirect. Insulin-like growth factor protein structure, similar to insulin y made in liver 25 an endocrine hormone, produced by target tissues. 4,98% bind to ito binding protein to protect. Ligf i is greater before growth; ige i is greater after birth by increases protein synthesis (m tor); v apoptosis (beds; increases transcription (map_k)
