ANPS 020 Lecture Notes - Lecture 23: Peritubular Capillaries, Efferent Arteriole, Waste Container

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The nephrons are intimately associated with capillaries: the peritubular capillaries and the vasa recta. Efferent arterioles of cortical nephrons drains into peritubular capillary beds. In juxtamedullary nephrons, efferent arteriole drains into vasa recta. Efferent arterioles give rise to peritubular capillary bed. Surround pct and dct in cortex: will reclaim most of the solutes and water from the filtrate. Urine formation and blood adjustment relies on key processes of filtration, reabsorption, and secretion. Glomerular filtration dumps cell-free and protein-free blood filtrate into the container. Tubular reabsorption reclaims what the body needs to keep. Tubular secretion selectively adds to the waste container. The kidneys will process 180 l of blood derived from fluid a day. But only 1. 5 l leaves the body as urine. We only call it urine after all processing is complete. 3 layers of filtration membrane: fenestrated endothelium of glomerular capillary, basement membrane, filtration slits between foot processes of podocytes.

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