L07 Chem 481 Lecture 16: Lecture 16
5 Mar 2017
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Document Summary
F6p more economical because will divide into 2, 3 carbon molecules. G6p would form 1 4 carbon molecule and 1 2 carbon molecule. Reaction is pulled forward by consuming the available g3p. Only half of the 3 carbon products go thru this reaction. Part of the g3p shuttle which is coupled with ad -> fadh2 on mitochondrial g3p dehydrogenase. The g3p shuttle is regulated by how well the electron transport chain functions. For any given g3p molecule, the g3p s carbon 1 could come from carbon 3 or carbon 4 of glucose depending on if it came from dhap or directly from glucose. Amount of energy released when a phosphorylated compound transfers its phosphoryl group to water. Gapdh (glyceraldehyde 3-phosphate dehydrogenase) produces first high-energy intermediate in glycolysis. 1,3 bpg has a greater phosphoryl transfer potential than atp. Gapdh can be thought of as catalyzing 2 processes.
