L07 Chem 481 Lecture 12: Lecture 12 (correct numbering)
10 Mar 2017
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Forces components to be in a certain conformation. Each pair of conformations forces the other subunits into a specific conformation. There are 10 c units in the spinning wheel = c10. The c10 part actually spins which allows the subunit which gets the subunit to spin. G is the difference in stability between the products and the reactants. Atp -> adp + pi has very negative g because it has less repulsion and breaks a high energy bond. The pi can go far away from adp to be very stabilized. Complex v forms interactions with atp, so that atp binds to complex v with high affinity, then it helps to stabilize atp, so hydrolyzing atp into adp has very little difference in stability. The affinity for atp is 7 orders of magnitude greater than for adp. Adp and pi are rapidly exchanging os with h2o and atp.
