MCIM 326 Study Guide - Final Guide: Polynucleotide, Pyrimidine, Ribose
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16 Dec 2015
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The linear density of dna is roughly 2x106 molecular weight units per micrometer, and the average weight of a base pair is 660. If a viewer watched an object move along a right- handed helix, the object would follow a clockwise path and move away from the viewer. A counterclockwise path would cause the object to move away in a left-handed helix. A nuclease is an enzyme capable of breaking a phosphodiester bond. It could not because there would be no gree ends, which an exonuclease requires. The supercoiling is ireellevant; only the fact that it is covalently closed is important: which of the following operations will induce formation of a supercoil: Joining the ends of a linear dna and doing nothing else; Twisting the two ends of a linear dna and then joining the ends together; Only twisting followed by joining: analysis of a dna sample from a bacterium indicates that 18% of the bases are a.
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QUESTION 1. Compared to eukaryotic genomes, only prokaryotic genomes:
A. contain DNA organized by histones. |
B. contain usually one, circular chromosome. |
C. contain plasmid DNA. |
D. have chromosomes contained in a nucleus. |
QUESTION 2. Azathioprine is a drug that may be prescribed to transplant recipients to reduce the chance of tissue rejection reactions. In its active state, it acts as a purine analogue, inhibiting DNA biosynthesis. This means that 6-mercaptopurine will be inserted in place of a purine containing nucleotides during DNA replication. Given this drug's mode of action, you would expect it to be incorporated into DNA in place of:
A. nucleotides containing guanine or cytosine. |
B. nucleotides containing adenine or thymine. |
C nucleotides containing adenine or guanine. |
D. nucleotides containing guanine nucleotide or uracil. |
QUESTION 3. RNA is distinguished from DNA because only RNA:
A. typically exists as a single-stranded molecule. |
B. has a 3' to 5' directionality. |
C. is composed of nucleotides that contain the sugar deoxyribose. |
D. is composed of nucleotides that contain the nitrogen bases T, C, G, and A. |
QUESTION 4. How are RNA nucleotides different from DNA nucleotides? To be marked correct, you'll need to select all true statements, as there may be more than one correct answer.
A. RNA nucleotides do not contain thymine. |
B. RNA nucleotides use the sugar ribose, while DNA nucleotides do not. |
C. RNA nucleotides lack phosphate. |
D. RNA nucleotides incorporate pyrimidine nitrogen bases, while DNA nucleotides only incorporate purine nitrogen bases. |