BIOL 121 Study Guide - Midterm Guide: Sister Chromatids, Nuclear Membrane, Kinetochore

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BIOL 121 Full Course Notes
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BIOL 121 Full Course Notes
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Cohesins are proteins made of 3 subunits that hold sister chromatids together. Microtubules are proteins that transport dna to the poles. Condensins are proteins that encircle dna and stabilize loops of it to make it shorter. Made of 3 subunits and are ring-shaped. Nuclear lamins are proteins involved in the formation of a nuclear envelope. If something isn"t right, the cell goes through apoptosis (controlled destruction caused by p53, a tumour suppressor) . Damage to dna causes dephosphorylation and activation of mpf is blocked. Anaphase is delayed until all the kinetochores attach to the spindle fibres. Cells that fail a checkpoint: proteins that shouldn"t be active, are, tumour suppressing genes can"t shut down the cell cycle. Nuclear division that halves the chromosome number (diploid haploid). Crossing over occurs during late prophase i. Chromatids break and rejoin at each chiasma. Different alignments of chromosomes on the metaphase plate. Create new combinations of paternal and maternal chromosomes in daughter cells.

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