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PSY352H5 Study Guide - Final Guide: Synaptic Vesicle, Optimal Foraging Theory, Net Energy Gain


Department
Psychology
Course Code
PSY352H5
Professor
Robert Gerlai
Study Guide
Final

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Explain the three types of selection forces we discussed? (5 marks)
- Directional Selection: occurs when a certain extreme trait becomes much more adaptive and beneficial to species
survival..
- Stabilizing Selection: would occur when neither extreme of the trait is beneficial but the normal or middle
variation of the trait is
- Disruptive Selection: occurs when both extremes of the trait are adaptive and beneficial to species survival.
-
1. Please explain whether scientists think evolution has a purpose? --OR --On the basis of Darwinian Theory, do you
think that appearance of species was just a lucky coincidence or was it inevitable that Homo sapiens have
evolved? (3 marks)
- Is purposeless change resulting from random variation
- Mutation ( genetic variation) is the basis of variability upon which natural slection works.
- Evolution is change in allele frequencies from generation to generation.
- It doesn’t work toward a specific direction species must move, it’s completely random.
- However, species if able to adapt to the environment and reach their reproductive age, will survive.
- There have been trillions of accidental events that led to the existence of all current life on the planet.
- Homo sapiens have evolved to cope with certain environments and perform particular tasks.
2. Briefly describe the function and structure of DNA. (5 marks)
DNA is a base pair helical molecule with two twisting sugar-phosphate back bones attached to each other by pair
of nucleotides
Have 4 building blocks (nucleotide bases): Adenine, Thymine, Guanine, and Cytosine.
5”prime (beginning) and 3”prime (end) is the position of basis relative to sugar molecules in DNA backbone.
it’s structure is a mechanism for heredity
Info in DNA guides the cells to make new proteins( aminoacids)
that determine all of our biological traits that get passed to next generations.

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3. What is an action potential and how is it generated? Please describe the process? (6 marks)
The action potential is the change in the cells voltage. Is a quick reversal of the negative resting potential from -
65mv to +40mv
it can be inhibitory or excitatory. An action potential can be generated in numerous ways.
The integration of EPSP and IPSP would generate a potential. All or none phenomenon (it either occurs or it
doesn’t)
When electrical signals inside neurons travel through to the target neuron. These signals can be carried out by
TEMPORAL or SPATIAL summation.
an excitatory postsynaptic potential (EPSP) is a temporary depolarization of postsynaptic membrane potential caused by
the flow of positively charged ions into the postsynaptic cell. They are the opposite of inhibitory postsynaptic potentials
(IPSPs), which usually result from the flow of negative ions into the cell or positive ions out of the cell
Process:
1. The electrical signals(EPSP) brings the neuron to threshold; Na+ channels will open and a lot of Na+ will rush into
the cell making the cell positive inside (depolarization). (rising phase)
2. At the peak of the potential Na+ channels will start closing and K+ channels will open. (overshoot phase)
3. K+ will exit the cell; hyperpolarizing it. (repolarising phase)
4. K+ will exit too much (undershoot phase)
5. All K+ will close ( recovery phase)
6. Cell will return to resting potential. (-65mv)
4. Please revise what happens when an action potential reaches presynaptic terminal and how the signal is
transmitted to postsynaptic terminal. (8 marks)
Communications among neuron occurs at specialized junctions called “synapses”.
most common type of synapse is the chemical synapse
Synaptic transmission begins in a chemical synapse in a Nervous system, when a nerve impulse reaches the
presynaptic axon terminal.
depolarization of presynaptic membrane initiates sequence of events leading to transmitter release and activation
of receptors on post synaptic membrane.
Some principle molecules and organelles necessary for the release of neurotransmitters :
o Ca2+ channels, and Ca2+ ions.
o synaptic vesicles
o mitochondria
o transmitter molecules
o synaptic cleft
o post synaptic receptors

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PROCESS:
i) when presynaptic neuron is depolarizedvoltage gated calcium channels open and calcium ions rush into the
axon terminal
ii) some of these calcium ions bind to protein on synaptic vesicles membrane( synaptotagmin)
iii) These synaptic vesicles then move to the presynaptic membrane and both (synaptic vesicle membrane and
presynaptic membrane are drawn together by SNAREs)
iv) once these two are fused, they release neurotransmitter molecules into the synaptic cleft
v) These transmitter molecules bind to receptor molecules in post synaptic membrane. Excitation or inhibition
depends on the particular neurotransmitters and their receptor combination.
vi) receptors open, Na+ comes into the cell generating Excitatory post synaptic response
vii) AChE in the synaptic cleft, breaks down ACh >>A +Ch
viii) release of receptors causes channels to close
ix) left over neurotransmitters from the cleft are taken back to presynaptic terminal by TRANSPORTERS
(REUPTAKE)
x) They are refilled by synaptic vesicles so they can be recycled.
xi) a spike in presynaptic cell, will stimulate a spike in post synaptic cell.
5. What is LTP? How is it induced and measured? What is its relevance to behaviour? (6 marks)
Long term potentiation is the persistent increase in synaptic strength following high frequency stimulation of a
chemical synapse.
Synapses that have undergone LTP tend to have stronger electrical responses to stimulation than other synapses.
Increase in synaptic strength or potentiation lasts a very long time compared to other processes that affect
synaptic strength
An increase likelihood of cells firing A.P/ in response to a constant synaptic input LTP long lasting and involved in
many memory formations
Contributes to learning and memory.
6. Explain why behavioural characteristics don’t often follow Mendelian Inheritance? (4 marks)
There is a tendency to think that there are genes for particular behaviour.
Some part of genetic material of individuals causes variation in physical structure of that behaviour
That structure in turn causes specific behaviour changes under particular combination of env. Circumstances.
Thus, behaviour is influenced by BOTH env. And genetics.
For law of dominance: not all alleles are dominant or recessive one has alleles that express co-dominance and
incomplete dominance where both traits are visible to some extent.
Law of independent assortment: some genes are linked which would imply that when asserting they would assert
together. i.e. A+B-> C
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