CHEM C130 Study Guide - Midterm Guide: Accessible Surface Area, Ramachandran Plot, X-Ray Crystallography

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8 Jan 2019
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Please write your name on the first page: find the letter below that best matches the following statements. Draw the structure of 3"-deoxyadenosine 5"-triphosphate (6 pts. ) __m__ commonly occurs at the end of rna stems. __c__ reflects the overall quality of a nmr structure. __e__ determined by van der waals contacts in a tripeptide. __a__ commonly occurs where three rna strands come together. __o__ each base pair displays a unique pattern of h-bond donors and acceptors. __q__ used to define atoms on the inside and outside proteins. This molecule is the triphosphate form of a drug, cordycepin, which is an inhibitor of poly-a synthesis at the 3" end of mrna. At high concentrations it affects all rna synthesis. What is the basis of inhibition? (3 pts. ) When it gets incorporated into rna, the chain can"t be elongated because there is no 3" nucleophile. Why does this molecule (cordycepin triphosphate) fail to inhibit dna synthesis? (3 pts. )