BIOL 142 Study Guide - Midterm Guide: Phosphodiester Bond, Reverse Transcriptase, Edward Tatum
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Chi-square test to establish linkage: null hypothesis: genes are unlinked (syntenic) and 1:1:1:1 phenotypic ratio is expected, assumptions: monogenic, independent assortment, complete dominance, need to include critical value, p-value, fail to reject or reject the null, significance level. Steps to a three-point map of linked loci. A: determine configuration of original parent chromosomes (cis or trans) Types of bacteria and viruses - diseases between e. coli cells. In humans: tuberculosis (bacteria, herpes simplex (viruses, ebola (virus, bubonic plague (bacteria) In plants : tmv (tobacco mosaic virus, pseudomonas, burkholderia. Bacterial genome in prokaryotes: different types, bacterial chromosomes single, circular location of essential genes (vertically transmitted, plasmids (not part of the bacterial genome) single, circular location of nonessential genes (not necessarily transmitted vertically) a) Important and provide a selective advantage: genome packaged by supercoiling, folding, and attachment, no nucleus, have a nucleolus, recombination and co-integration.
