BIOL 1108 Study Guide - Midterm Guide: Genotype Frequency, Allele Frequency, Genetic Variation

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5 Feb 2019
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And genotypic differences can be examined at the dna sequence level. Population genetics is the study of patterns of genetic variation. Genetic variation in humans is low compared to other species, meaning the gene pool is smaller. Mutation and recombination are the two sources of genetic variation. Germline mutations affect future generations whereas somatic mutations do not, and they can be neutral, deleterious, or advantageous. Allele frequencies contribute the information needed about patterns of genetic variation and how it affects the evolution of a population. To understand patterns of genetic variation, we require information about allele frequencies. Genotype frequencies can help us determine allele frequencies, and both of these types of frequencies can be measured by observable traits, gel electrophoresis, and dna sequencing. Early population geneticists relied on observable traits and gel electrophoresis to measure variation. Dna sequencing is the gold standard for measuring genetic variation. 21. 3 evolution and the hardy - weinberg equilibrium.

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