BIO206H5 Chapter Notes - Chapter 11: Phospholipid, Cytosol, Pathogenic Bacteria

• School: UTM
• Department: Biology
• Course: BIO206H5
• Professor: George S Espie

Document Summary

Lipid bilayer: phosphatidylcholine: most common type of phospholipid in cell membrane. Shorten chain length increases fluidity because it reduces tendency of hydrocarbon tails to interact with one another. Cholesterol molecules are short and rigid and fill in spaces caused by kinks thereby reducing fluidity: phospholipids are manufactured by enzymes bound to er facing cytosol. Deposit phospholipids in cytosolic half of bilayer. Enzymes called flippases are used to transfer specific phospholipids to other side of bilayer: glycolipids. Located mainly in noncytosolic half of plasma membrane: sugar groups face exterior of cell. Integrins: link intracellular actin filaments to extracellular matrix proteins. Receptors: platelet-driven growth factor receptor: binds extracellular pdgf and generates intracellular signals that cause the cell to grow and divide. Enzymes: adenylyl cyclase: catalyzes production of camp, integral membrane proteins: directly attached to membrane, peripheral membrane proteins protein attached, membrane spanning segments. Polypedtide backbone is hydrophilic: form h-bonds with each other, bonding maximized if a helices, pores.