BIOSC-116 Chapter Notes - Chapter 2: Pleural Effusion, Pulmonary Pleurae, Oncotic Pressure

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Normal pleural space anatomy and physiology as it relates to the pleural circulation. During embryonic development, the lungs grow into two balloon-like structures of mesothelial origin in the chest, which form the pleural surfaces. Both the parietal and visceral pleura are made of layers of collagen and elastin covered by a single cell layer of mesothelium. Only the parietal pleura are innervated (& gets all the lymphatic bitches) The arterial supply of the pleura arises from the systemic circulation. Venous drainage is into the la, which means that at elevated la pressures you get pleural effusions. Remember that intrapleural pressure is normally negative (around -5 cm. In healthy individuals, fluid moves into the parietal space from both parietal and visceral pleural capillaries. Fluid is then reabsorbed through large stoma in the parietal pleura which drain into the lymphatic system. Pleural symphysis: fusing of visceral and parietal pleura - doesn"t affect lung volume or gas exchange.

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