ANSC 4009 Chapter : Ansc 3010 Chapter 4 Assessing Nutrient Content Of Feeds Handouts
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Dna is the instructions (program) that tell the cell what to do. Molecular genetics: the protein vs. dna debate - 16. 1. 1. >>>>>>the study of metabolic defects provided evidence that genes lead to proteins. Archibald garrod first proposed this relationship in 1909. Inherited diseases were the result of the lack of an enzyme. Continuing to link genes to chemicals: muller, beable, and tatum - 16. 1. 2. The suggestion of garrod were confirmed in the 1930"s. George beadle and edward tatum conducted experiment with yeast, neurospora crassa, and demonstrated that different mutants (generated by x-rays) had the pathway of arginine (an amino acid) synthesis blocked at different steps (see fig. The mutants were auxotrophs that required added nutrients. Beadle and tatum deduced that the 3 different mutant types each lacked a different enzyme in the pathway that synthesizes arginine. From these results they formulated the one gene-one enzyme hypothesis. This has since been modified to the one gene-one polypeptide hypothesis because:
