SOCL 3501 Chapter : SOCL 3501 Fa12 02 Defining Deviance Part 2
Document Summary
Hemoflagellates ii leishmania sp: obligate intracellular parasites, heteroxenous, salivarian transmission, zoonotic organism: dogs, rodents are major reservoir hosts, there are many species, distributed: old world - europe, asia, africa and new world : americas species. If they are phagocytosed by neutrophils, they will be killed. Life cycle: sand fly takes blood meal ingesting parasitized cell, amastigotes transform into promastigote stage midgut, divide in midgut and migrate to proboscuis. (in mouthparts parasite produce a gell, that blocks sandfly gut, causing sandfly to regurgitate. This removes plug and deposits the entire number of promastigotes into the bite wound. This delivers the promastigotes into the bite wound: promastigotes are phagocytized by macrophages, promastigotes transform into amastigotes inside macrophages, amastigotes multiply in cells 9including macrophages of tissues). Leishmaniasis: three major disease syndromes: cutaneous leishmaniasis: oriental sore (delhi ulcer, jericho boil, baghdad boil) chiclero"s ulcer: (ear lesion in new world0, mucocutaneous leishmaniasis: espundia, uta (new world terms only, visceral leishmaniasis: kala-azar (black fever)
