BIOL 260 Chapter Notes - Chapter 4.3: Base Pair, Dna Ligase, Telophase
Document Summary
The fundamental steps of the replication process are as follows: 1. ) the double helix unwinds from the histones, 2. ) Dna helicase (an enzyme) opens up the helix, exposing its nitrogenous bases, like a zipper. The point where the dna is opened up is called the replication fork: 3. ) Dna polymerase moves along the strand and matches the bases with its corresponding counterpart. On one strand, the dna polymerase moves toward the replication fork and makes a long, continuous, new strand of dna to complement the old one. On the other strand, dna polymerase moves away from the replication fork and copies only a short segment of dna at a time. The segments are joined together by dna ligase. Each of the new strand has an old helix and a new helix (semiconservative replication: 4. ) While dna is synthesized in the nucleus, new histones are synthesized in the cytoplasm.
