BIOL121 Lecture Notes - Lecture 14: Triiodothyronine, Somatomedin, Glycogen

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Control and coordinate body processes and therefore preserves homeostasis. Nervous system: each nerve = few cells, fast to act, short lived, stops when stimulus stops. Endocrine system: hormone = wide dispersal, longer to act, longer lived, effects can persist. May have same chemical messengers: e. g. Endocrine: hormones: no duct and therefore is direct to the blood stream, e. g. insulin and glucagon. Exocrine: duct and therefore leads to lumen of the organ, e. g. digestive enzymes. Specific target: specific receptor, most hormones affect only a few types of cells. Paracrine (local: released to extracellular fluid, diffuse locally; still needs the receptor. Each cell can respond to many hormones. Saturation: additional hormone has no increase effect. Cells continually synthesise and degrade receptors: regulate hormone sensitivity. Amino acid derivatives: form single amino acid, e. g. Lipid based: similar structure to cholesterol, e. g. Lipid soluble can diffuse through: e. g. Hormone binds to receptor in/on membrane: hormone is first messenger. This activates: second messenger inside cell, e. g.

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