BIOL126 Lecture Notes - Lecture 4: Thymosin, Anterior Pituitary, Adrenocorticotropic Hormone

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10 Aug 2018
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Organs, tissues and cells of the endocrine system. Location: nervous system: the major glands of the endocrine system are the hypothalamus, pituitary, thyroid, parathyroid, adrenals, pineal body, the pancreas, and the reproductive organs (ovaries and testes). Comparison of the roles of the nervous and endocrine systems in homeostasis. Integrates tissue by a network of cell connections: neurotransmitters act as local chemicals to transfer information from cell to cell, short distance, fast signal transduction (milliseconds seconds) Hormones act as blood-borne chemicals for information transfer. Long distance fast/slow signal transduction (milliseconds seconds minutes hrs days yrs. ) Long-range messengers secreted into blood by endocrine glands in response to appropriate signal. Peptide hormones (proteins and peptides: hydrophilic hormones, stored in secretory granules, majority of hormones are peptide hormones (e. g. insulin, gh) Amine hormones: synthesised from a single amino acid, often from tyrosine e. g. Catecholamines: hydrophilic hormones such as adrenaline, thyroid hormone. Lipophilic hormones e. g. cortisol, aldosterone, sex hormone, vitamin d.

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