BMS129 Lecture Notes - Lecture 10: Osteoclast, Hydroxylapatite, Central Canal

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8 May 2018
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BMS129 Week 10 - Bone - Bone Tissue
This topic is split into 2 lectures:
1. Bone tissue
2. Skeletal system and joints
General advice: read textbook references, lecture slides, any relevant textbook
questions, and assess learning against learning outcomes.
Lecture 1 - Bone Tissue
Recommended readings
: Saladin CH 7 pp 207-225 and the first lecture of the bone
lectures.
When finished with this section, test your knowledge against these learning outcomes,
and go back to revise the ones you are unfamiliar with.
1. List 5 functions of the skeletal system
2. Describe the 4 different bone shapes with examples for each
3. Describe the general structure for long and flat bones
4. List & describe the cell types and the matrix of bone tissue
5. Describe the histology of compact and spongy bone
6. List & describe the two methods of bone formation
7. Explain how mature bone continues to grow and also explain Wolff’s
8. Discuss how the body maintains calcium homeostasis
List 5 functions of the skeletal system
1. Support
2. Protection (of brain, spinal cord, heart, lungs)
3. Movement
4. Electrolyte balance (calcium and phosphate ions)
5. Acid-base balance (blood buffer)
6. Blood formation (red bone marrow → produce blood cells)
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Describe the 4 different bone shapes with examples for each
Shape
Description
Example
Long
Levers for muscles to pull on
Length > width
Femur, radius, phalanges
Short
Length = width
Limited motion, glide across one another
Carpal and tarsal
Flat
Thin, parallel surfaces
Parietal and frontal bones,
scapula
Irregular
Complex shapes
Short, flat, notched, ridged surfaces
Vertebrae, facial bones of
skull
Remember: long short flat irregular, femur carpal scapula facial bones
Test yourself: describe 2 different bone shapes, giving examples
Describe the general structure for long and flat bones
Long bones
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Document Summary

Bms129 week 10 - bone - bone tissue. This topic is split into 2 lectures: bone tissue, skeletal system and joints. General advice: read textbook references, lecture slides, any relevant textbook questions, and assess learning against learning outcomes. Recommended readings : saladin ch 7 pp 207-225 and the first lecture of the bone lectures. List 5 functions of the skeletal system: support, protection (of brain, spinal cord, heart, lungs, movement, electrolyte balance (calcium and phosphate ions, acid-base balance (blood buffer, blood formation (red bone marrow produce blood cells) Describe the 4 different bone shapes with examples for each. Remember: long short flat irregular, femur carpal scapula facial bones. Test yourself: describe 2 different bone shapes, giving examples. Describe the general structure for long and flat bones. Middle layer: spongy bone and bone marrow. Test yourself: describe the general structure of long bones. List & describe the cell types and the matrix of bone tissue.

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