DASC20010 Lecture 14: LEcture 14

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Objectives: describe the estimation urine excretion and plasma clearance, describe the counter-current mechanism, explain the regulation of sodium reabsorption, explain the regulation of water reabsorption, describe the regulation of bladder control. Urine excretion and plasma clearance: clearance = filtered reabsorbed + secreted, amount that is going from the plasma into the urine, clearance rate = [urine] x urine flow rate / [plasma] Clearance rates: (gfr: possible for clearance rate to be higher than gfr- have some filtering and secretion of h, h, can measure ph of uring, para-aminohippuric acid (pah, filtered + secreted (-reabsorbed, pcr= renal plasma flow. Isotonic= 300 mmol/l: 200mmol/l difference with salt pump", 900 mmol/l difference between cortex and medulla. Description: vertical osmotic gradient in the human renal medulla, the osmolarity of the interstitial fluid throughout the renal cortex is isotonic as.

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