BCMB20002 Lecture Notes - Lecture 6: Beta Sheet, Ribonuclease, Enthalpy
3 Aug 2018
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Document Summary
Abundant, mostly on surface, redirect backbone (particularly for -sheets). (especially for antiparallel beta sheet) Residues i+1 and i+2 have different , angles. A hydrogen bond between the carbonyl of the first (i) and the nh of the fourth (i+3) stabilizes the turn. Proline often in position i+1, not flexible at phi angle; type ii turns often have. I+2 side chain pointing up, same side as carbon. The , angles vary for residue i+1 and i+2. In the reverse turn: it is irregular structure. , pairs for residue i+1, and i+2 in. Note: for a given turn the sequential residues i+1 and i+2 the , angles are different. The , angles occur in the allowed regions (or close) Steric restrictions limit the possible , angles. , of 0 ,0 is not possible; and +ve. Sheets and -helices are abundant elements of regular secondary structure. Regular structure is defined as residues that have repeating , angles ( -helix:
