BIOM20001 Lecture Notes - Lecture 22: Tumor Suppressor Gene, Bladder Cancer, Oncogene
Document Summary
22 cancer - oncogenes and tumour suppressor genes. Rates of (cid:272)a(cid:374)(cid:272)e(cid:396) i(cid:374) aus (cid:272)o(cid:374)siste(cid:374)t. total (cid:374)o. of (cid:272)ases is i(cid:374)(cid:272)(cid:396)easi(cid:374)g (cid:271)ut that"s due to increasing population. Of these over half were the big 5 cancers (breast, lung, prostate, bowel, melanoma) 2nd most common cause of death in 2010. 5 year relative survival for cancer patients increased from 47% to 66% Cancers that already had low survival showed little improvements (e. g. pancreatic from. 3% to 5% and lung cancer 9% to 14%) Cancer: abnormal and improperly controlled cell division resulting in invasive growths or tumours that spread. Sarcoma: collective term for cancers of connective tissue (bone, cartilage, fat, muscle, vascular tissues) Carcinoma: collective term for cancers of epithelial cells. Most common class of human cancers (e. g. lung, breast, bowel, prostate), accounting for 80% Cancer is a generic term used for a collection of over 200 diseases that are characterized by unregulated cell growth.
