BIOM20002 Lecture Notes - Lecture 17: Epiphyseal Plate, Diaphysis, Epiphysis
Document Summary
Surface of bone that make contact with other bone. Dense, irregular collagen fibres - high concentration of fibrous tissue. Forms discs (intervertebral discs), meniscus (in knee), labrum (in shoulder/hip sockets). It does not need a blood supply or a nerve supply (in general). Fibrocartilage (forms discs in intervertebral region) gets a blood and nerve supply on outer rim. If you strain and break menisci then repair is not easy because you only get blood supply on the outer rim. These condense to form bone (made from mesoderm) Bone first appears between weeks 6-8 of intrauterine life. Primary centre of ossification: blood supply invades cartilage in middle of shaft and deposits cartilage cells. Cartilage cells grow, swell making the tissue soft. Cartilage progressively replaced by bone, extending towards the ends (epiphyses) On outside of the bone (what becomes periosteum), cartilage cells become osteogenic cells. Bone simultaneously formed in periosteal and endosteal layers, to remodel the medullary cavity.
