PHYS20008 Lecture Notes - Lecture 17: Hemoglobin, Blood Plasma, Nitric Oxide

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Note: first bit of lecture is final respiratory system content not finished from last lecture. The rest of the lecture is respiratory challenges. 3 main things can change the shape of the curve (ie affect how much oxygen is allowed to dissociate and go to tissues in need): This is because co2 takes up o2 binding sites. These changes are important in certain areas of the body and at certain times (eg exercise) Anywhere where metabolic processes have increased in the body will result in a shift to the right on the curve. When blood reaches the lungs, ph, temperature and co2 should be at normal levels so haemoglobin can be reloaded byproduct of anaerobic metabolism. The exception to this is 2,3-dpg which is a compound made as a. It makes the curve shift to the right to make it more generous. However, 2,3-dpg is attached to the rbc so also takes effect in the lungs.

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