PSYC20006 Lecture Notes - Lecture 17: Neurotransmission, Hydrogen Bond, Electric Current

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10 May 2018

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Lecture 17

- Electric current flows down axon

- Fires in an all or none capacity

- Dynamic: synapses can disappear and be built up again

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- Phospholipid bilayer: receptors allow information to flow

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- Ion channels: gate for ions; charge of neuron firing → driven by total concentration of

negative or positive charged ions in cell

- Change in charge (electricity flows through) → ions are allowed to flow in and out of

the neuron rapidly → neurotransmitter docking on → will allow more or less ions to

flow through → direct and rapid impact on activity of neuron

- G protein-coupled receptors (second messengers): neurotransmitter docks on

outside → wont directly impact; allow energy to mediate a subsequent downstream

event; can trigger ion channel opening

- Receptor specificity: receptors are very selective (lock and key); each receptor can

generally only be activated by one neurotransmitter (or a drug that is designed to

mimic that neurotransmitter); they also have a very specific function/action → when a

neurotransmitter binds to the receptor this will trigger the same event every time

(either opening a channel or triggering a second messenger event)

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