PSYC20006 Lecture Notes - Lecture 20: Cortisol, Diagnostic And Statistical Manual Of Mental Disorders, Brainstem

• School: University of Melbourne
• Department: Psychology
• Course: PSYC20006
• Professor: All

Document Summary

The more serotonin manic happy state; less serotonin sad depressed state. E used to be in dsm iv. In post-mortem studies patients with depression had reduced number of serotonin receptors. A gene involved in the transportation of serotonin is linked to increased risk of developing depression. Tryptophan depletion (trd) induces transient depressive symptoms in recovered unmedicated depressed patients (and in some people without depression) [trd studies involve consuming a milkshake consisting of all amino acids except for. Tryptophan (the serotonin building block), this reduces available tryptophan leading to reduced synthesis of serotonin] Endless release of serotonin uninformative release. Ssri"s are very slow acting and often takes weeks for any therapeutic effects to be achieved. If taken orally the drug reaches the brain after approximately 1 hour after consumption and should block serotonin reuptake immediately once in the brain. Therefore, improved mood can not result directly from increased serotonin around the synapse.