PSYC20006 Lecture Notes - Lecture 7: Ank3, Bipolar Disorder, Fmr1

• School: University of Melbourne
• Department: Psychology
• Course: PSYC20006
• Professor: Stefan Bode

Document Summary

Incredibly small in size: but hundreds of parts of dna. Genetic variants: single nucleotide, difference at one nucleotide, one base is exchanged for another, e. g. changing an a to a g. Extra base pairs are inserted into a new place in the dna: deletion, a section of dna is lost, or deleted, block substitution, an area is changed. Inversion: where segment of a chromosome is reversed end-end, occurs when a single chromosome undergoes breakage and rearranges within itself, copy number, sections of the genome are repeated. Mutations: rare genetic variants, less than 1% of alleles, polymorphism, common, presence of genetic variation within a population, natural selection can occur within thios. Karyotype: karyotype, number and visual appearance of the chromosomes, xx, female, xy, male. In a planned experiment, the covariance can be controlled (and held at 0): h2 = varg/varp. In an experiment where there is no genetic variation, any variation in phenotype must be due to environment: or vice versa.