BIO1022 Lecture 9: Week 9

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-most have limited host range: the discovery of viruses. 1883 invisible pathogens noted in tobacco mosaic disease. Could filter out bacteria and still reproduce disease. -1935 tmv crystallized seen under em (invented 1931: viral ge(cid:374)o(cid:373)es are s(cid:373)all (cid:449)ith high ge(cid:374)e de(cid:374)sit(cid:455, virus classification. Viruses of the same genera share all major features of their life cycles and niches. -disease caused: the steps in viral replication. -maturation and release (cells may or may not lyse) - lysis or budding: viruses that infect humans. New strains can arise from reassorted genome fragments. Seasonal epidemics or global pandemics: e. g. smallpox (variola) virus. Spread by infected cells and by respiratory route lipid envelope. Systemic spread: viruses that infect humans and against which vaccines have been developed. -vaccinia (cowpox) protects against smallpox (variola virus) (cid:463)ed(cid:449)ard je(cid:374)(cid:374)er(cid:859)s (cid:272)o(cid:449)po(cid:454) experiment (cid:464) Eradi(cid:272)atio(cid:374) of s(cid:373)allpo(cid:454) de(cid:272)lared i(cid:374) (cid:1005)(cid:1013)(cid:1012)(cid:1004) (cid:894)last (cid:272)ase i(cid:374) (cid:858)(cid:1011)(cid:1011)(cid:895) Successful who program based on vaccination and quarantine.