BMS2021 Lecture Notes - Lecture 5: Brown Adipose Tissue, Glycogenolysis, Tachycardia
15 Aug 2018
School
Department
Course
Professor
Document Summary
Week 5 autonomic control of energy, exercise and metabolism. Describe the processes of neuron transmitter synthesis and storage specific to noradrenaline and adrenaline. Synthesized inside the nerve axon, stored within vesicles. Released by the nerve when an action potential travels down the nerve. Stimulation of both alpha and beta adrenergic systems. Cytoplasmic: dopa decarboxylase, dopamine hydroxylase (d h) Located in synaptic vesicles: reuptake into nerves. Most import immediate effect: enyzymic break-down. Sympathetic nervous system triggers a response = fight or flight. Actions: energy alertness, concentration, impulse anxiety, attention motivation. Smooth muscle (blood vessels, glands, gut, etc) Describe sympathetic nervous control of energy and metabolism. Smooth muscle relaxes/dilates to increase blood flow. Describe the tissues and receptors targeted by noradrenaline and adrenaline in energy and metabolism. Adrenaline and noradrenaline (cid:862)en(cid:272)ourages(cid:863) the (cid:272)onversion of energy stores (cid:894)gly(cid:272)ogen and fat(cid:895) to freely availa(cid:271)le fuels (cid:894)glu(cid:272)ose and free fatty acids. Stimulate glucose uptake into muscle (independent of insulin)
