PHY2011 Lecture Notes - Lecture 34: Brainstem, Pituitary Gland, Gastrocnemius Muscle

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Week 12 L3 -exam prep
Exam details
oTwo hours (+10 mins reading time)
oFour sections
oEach section worth 3.75 marks
Muscle contraction and function
o1. Illustrate the diagram for the active length force relationship in skeletal muscle.
Show the state of the contractile proteins at critical points on the curve, including
the Optimum length
o2. Describe how our myofilaments, actin and myosin interact throughout the stages
of the crossbridge cycle. Ensure that you include ATP, ADP, power stroke, troponin
and tropomyosin in your description process. It is recommended that you create
diagrams or a flow chart.
o3. Illustrate the normal excitation contraction coupling and cross-bridge cycling,
using diagrams of the neuromuscular junction with complete and appropriate labels
of critical structures. In your answer ensure to describe how depolarization of the
transverse tubules can trigger the release of calcium, breaking down the steps in a
diagram or flow diagram.
oUnderstand excitation contraction cycle process, how it produces force, and the
relationship between force and muscle length
Movement control
oMotor Units & Muscle sensors:
o1. How we grade our movements (vary force)
Recruitment
- Start with small, then intermediate then large
- Number of APs required to reach threshold depend on size of EPSPs
- More neurons contract as more APs reach a neuron
Rate coding (temporal summation)
- Still just increasing number of APs
- The faster the APs go to a muscle, the more the muscle contractions
sum
o2. How we monitor muscle changes and force and respond
Muscle spindles monitor muscle length
Golgi tendon organs monitor muscle force
oLocomotion
o1. Spinal cord generators of Locomotion
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Document Summary

Exam details: two hours (+10 mins reading time, four sections, each section worth 3. 75 marks. Illustrate the diagram for the active length force relationship in skeletal muscle. Show the state of the contractile proteins at critical points on the curve, including the optimum length: 2. Describe how our myofilaments, actin and myosin interact throughout the stages of the crossbridge cycle. Ensure that you include atp, adp, power stroke, troponin and tropomyosin in your description process. It is recommended that you create diagrams or a flow chart: 3. Illustrate the normal excitation contraction coupling and cross-bridge cycling, using diagrams of the neuromuscular junction with complete and appropriate labels of critical structures. Movement control: motor units & muscle sensors, 1. Number of aps required to reach threshold depend on size of epsps. More neurons contract as more aps reach a neuron. The faster the aps go to a muscle, the more the muscle contractions sum: 2.

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