PSY2061 Lecture Notes - Lecture 10: Jerky, Amyloid, Subthalamic Nucleus
21 Aug 2018
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Document Summary
Contusions from closed- head injuries occur when the brain slams against the inside of the skull (blood from such injuries can accumulate in the subdural space and severely distort the surrounding neural tissue). Thus, when the egg is fertilized, there are three chromosome 21s rather than 2 in the zygote). Consequences: characteristic disfigurement, intellectual impairment, troublesome medical complications. It was once assumed that cells die from injuries (necrotic). But now, it seems that if cells are not damaged too severely, they will attempt to marshal enough resources to commit suicide. Describe epilepsy, parkinson"s disease, huntington"s disease and alzheimer"s disease. Huntington"s disease: progressive motor disease and very rare (1 in 10,000), has a simple genetic basis and always associated with severe dementia, first common sign: increased fidgeting. Transgenic mouse models of alzheimer"s disease: transgenic = animals into which genes of another species have been introduced.
