LQB185 Lecture Notes - Lecture 10: Dense Irregular Connective Tissue, Bone Marrow, Hyaline Cartilage

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Week 10: The Skeletal System

➢ Skeletal System Functions:

1. Support

2. Protection

3. Assistance in movement

4. Mineral homeostasis (storage and release)- Ca+ and phosphorus,

99% of ody’s aliu

5. Blood cell production- red bon marrow in certain bones produces red

blood cells, white blood cells and platelets (HEMOPOIESIS)

6. Triglyceride storage- yellow bone marrow consists of adipose cells

that store triglycerides (energy reserve)

➢ Diaphysis- oe’s shaft

➢ Epiphyses- proximal and distal ends of the bone

➢ Metaphysis- regions between the diaphysis and the epiphyses

➢ Articular Cartilage- thin layer of hyaline cartilage converging the part of

the epiphysis.

➢ Periosteum- connective tissue sheath that surrounds the bone surface.

Consists of a OUTER fibrous layer of dense irregular connective tissue

and an INNER osteogenic layer of cells.

➢ Medullar Cavity- hollow cylindrical space within the diaphysis that

contains fatty yellow bone marrow and blood vessels. Minimises bone

weight

➢ Endosteum- thin membrane that lines the medullar cavity, single layer

of bone-forming cells and connective tissue.

➢ Extracellular matrix

- 15% water

- 30% collagen fibres

- 55% crystallized mineral salts (mostly calcium phosphate and Calcium

hydroxide= Hydroxyapatite

- This crystalizing causes tissue to harden called Calcification

➢ A oe’s hardness depends on crystallized inorganic mineral salts

➢ A oe’s flexibility depeds o it’s ollage fires

➢ 4 types of cells found in bone tissue

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1. Osteogenic cells- unspecialized bone stem cells, undergo cell division

that develop into osteoblasts

2. Osteoblasts- bone-building cells, secrete collagen fibres and other

organics to build the extracellular matric of bone tissue. They trap

themselves in their own secretion and become osteocytes

3. Osteocytes- mature bone cells, maintain daily metabolism

4. Osteoclasts- huge ells, it’s plasa erae is deeply folded ito a

ruffled border that releases powerful lysosomal enzymes that digest

proteins of extracellular bone matrix= Resorption

➢ Osteoblasts- build bone

➢ Osteoclasts- carve out bone

➢ 80% compact bone, 20% spongy bone

➢ Compact Bone Tissue

- Makes up bulk of diaphysis

- Provides protection and support resists from stresses

- Comprised of repeating structural units called Osteons

- Each Osteons consists of concentric lamellae arranged around a

central canal

- Concentric lamellae are circular plasters of mineralized extracellular

matrix of increasing diameter

➢ Spongy Bone Tissue

- does not contain osteons, provide nourishment to the osteocytes

Blood and nerve supply of bone

➢ Passes into bones from the periosteum

➢ Periosteal arteries enter the diaphysis through perforating canals

➢ Nutrient artery passes through a hole in compact bone called nutrient

foramen

➢ Metaphyseal arteries enter the metaphysis of a long bone

➢ Epiphyseal arteries enter the epiphyses of a long bone

Bone Formation

➢ Bone forms= Ossification/Osteogenesis

➢ 2 ways of bone formation in birth.

1. Intramembranous ossification- bones form directly within

mesenchyme

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Document Summary

Skeletal system functions: support, protection, assistance in movement, mineral homeostasis (storage and release)- ca+ and phosphorus, 99% of (cid:271)ody"s (cid:272)al(cid:272)iu(cid:373: blood cell production- red bon marrow in certain bones produces red blood cells, white blood cells and platelets (hemopoiesis, triglyceride storage- yellow bone marrow consists of adipose cells that store triglycerides (energy reserve) Epiphyses- proximal and distal ends of the bone. Metaphysis- regions between the diaphysis and the epiphyses. Articular cartilage- thin layer of hyaline cartilage converging the part of the epiphysis. Periosteum- connective tissue sheath that surrounds the bone surface. Consists of a outer fibrous layer of dense irregular connective tissue and an inner osteogenic layer of cells. Medullar cavity- hollow cylindrical space within the diaphysis that contains fatty yellow bone marrow and blood vessels. Endosteum- thin membrane that lines the medullar cavity, single layer of bone-forming cells and connective tissue. 55% crystallized mineral salts (mostly calcium phosphate and calcium hydroxide= hydroxyapatite.

Related Questions

Question 1.1. (TCO 1) Moving from the elbowtoward the wrist is an example of moving in a _____ direction.(Points : 4)

distal
lateral
medial
proximal

Question 2.2. (TCO 1) The left and rightpleural cavities are part of this cavity. (Points : 4)

Abdominal
Pelvic
Dorsal
Thoracic

Question 3.3. (TCO 1) The _____ separatesanterior and posterior portions of the body. (Points : 4)

transverse plane
sagittal plane
parasagittal plane
frontal plane

Question 4.4. (TCO 1) A parasagittal plane_____. (Points : 4)

separates superior andinferior portions of the body
separates right and leftportions of the body
misses the midline,separating right and left portions of unequal size
separates anterior andposterior portions of the body

Question 5.5. (TCO 1) Which of the followingterms is not used to define the structure that separatesthe contents of a human cell from its surrounding medium? (Points :4)

Cell wall
Cell membrane
Plasma membrane
Plasmalemma

Question 6.6. (TCO 1) Approximately 60-80% ofa living cell is made up of _____. (Points : 4)

water
oxygen
lungs
potassium

Question 7.7. (TCO 2) Stratified cuboidalepithelia would be found _____. (Points : 4)

lining the urinarybladder
lining the ducts thatdrain sweat glands
lining kidneytubules
lining the stomach
at the surface of theskin

Question 8.8. (TCO 2) The layer of theepidermis that contains stem cells undergoing mitois is the _____.(Points : 4)

stratum corneum
stratum basale
stratum granulosum
stratum spinosum

Question 9.9. (TCO 2) The tissue that alwayshas a free surface exposed to the internal or external environmentis the _____. (Points : 4)

epithelial tissue
connective tissue
muscle tissue
neural tissue

Question 10.10. (TCO 2) The code to make aparticular protein is a gene located on a _____. (Points : 4)

tDNA molecule
RNA molecule
DNA molecule
tRNA molecule

Question 11.11. (TCO 2) The lipid bilyaer ofthe plasma membrane is constructed largely of _____ with smalleramounts of cholesterol and glycolipids. (Points : 4)

cholesterol
neutral fats
phospholipids
fat-soluble vitamins

Question 12.12. (TCO 2) A group of similarcells and their intercellular substances specialized to perform aspecific function is a(n) _____. (Points : 4)

cell
tissue
organ
atom

Question 13.13. (TCO 3) The _____ of sweat isproduced by the action of bacteria feeding on the sweat. (Points :4)

color
odor
salt
nitrates

Question 14.14. (TCO 3) An acquired skindisease resulting in irregular patches of skin of various sizes andcompletely lacking pigmentation is known as _____. (Points :4)

albinism
impetigo
vitiligo
ringworm

Question 15.15. (TCO 3) Squamous cellcarcinoma arises from this layer of the skin. (Points : 4)

Stratum spinosum
Stratum corneum
Stratum granulosum
Stratum basale

Question 16.16. (TCO 3) The primary purpose ofsensible perspiration is _____. (Points : 4)

to heat internal bodyorgans
to heat the skin
for evaporativecooling
to get rid of bodywaste
to elevate bodytemperature

Question 17.17. (TCO 3) Sweating is anevaporation process that _____ the body. (Points : 4)

cools
heats
has no effect on
dries the body

Question 18.18. (TCO 3) When the _____ musclecontracts, it causes the hair to stand on its end. (Points :4)

vellus
terminal hair
rrrector pili
arrector pili

Question 19.19. (TCO 4) The formation of redand white blood cells by the red bone marrow is known as _____.(Points : 4)

hematopoiesis
periostesis
mastication
cartilage

Question 20.20. (TCO 4) Yellow bone marrowcontains a large percentage of _____. (Points : 4)

fat.
blood-formingclots.
elastic tissue.
Sharpey's fibers.

Question 21.21. (TCO4) The shaft of a longbone is called the _____. (Points : 4)

physis
epiphysis
diaphysis
metaphysis
lamella

Question 22.22. (TCO 4) The boundaries betweenskull bones and between immovable joints are _____. (Points :4)

foramina
fontanels
lacunae
sutures

Question 23.23. (TCO 4) The _____ is theexpanded prominence of the upper hip bone. (Points : 4)

sacrum
coccyx
pubis
iliac crest

Question 24.24. (TCO 4) The _____ is afibrovascular membrane that covers a bone. (Points : 4)

endosteum
yellow bone marrow
periosteum
compact bone marrow

Question 25.25. (TCO 5) The bones that formthe wrist are the _____. (Points : 4)

carpals
tarsals
metatarsals
phalanges

Question 26.26. (TCO 5) The following isnot
a structure found on the ishium. (Points : 4)

Superior ramus
Inferior ramus
Lesser sciaticnotch
Superior body

Question 27.27. (TCO 5) The side walls of thevertebral foramen are formed by the _____. (Points : 4)

centrum of thevertebrae
spinous process
pedicles
laminae

Question 28.28. (TCO 5) The largest facialbones are the _____. (Points : 4)

palatine bones
nasal bones
lacrimal bones
maxillary bones

Question 29.29. (TCO 5) The bone in directcontact with the first metatarsal (big toe) is the _____. (Points :4)

medial cuneiform
lateral cuneiform
cuboid
calcaneus

Question 30.30. (TCO 5) The antebrachium iscomposed of which of the following two bones? (Points : 4)

The radius and theulna
The humerus and theclavicle
The scapula and theclavicle
The humerus and theradius

Question 31.31. (TCO 6) A joint united bydense fibrocartilaginous tissue that permits a slight degree ofmovement is a _____. (Points : 4)

suture
syndesmosis
symphysis
gomphosis

Question 32.32. (TCO 6) Articular cartilagefound at the ends of the long bones serve to _____. (Points :4)

attach tendons
produce red blood cells(hemopoiesis)
provide a smooth surfaceat the ends of synovial joints
form the synovialmembrane

Question 33.33. (TCO 6) The cruciate ligamentsof the knee _____. (Points : 4)

tend to run parallel toone another
also are calledcollateral ligaments
prevent hyperextension ofthe knee
assist in defining therange of motion of the leg

Question 34.34. (TCO 6) Menisci refer to_____. (Points : 4)

cavities lined withcartilage
small sacs containingsynovial fluid
semilunar cartilagepads
tendon sheaths

Question 35.35. (TCO 6) Synovial fluid ispresent in joint cavities of freely movable joints. Which of thefollowing statements is true about this fluid? (Points : 4)

It contains onlyenzymes.
It contains lacticacid.
It contains hyaluronicacid.
It contains hydrochloricacid.

amaranthworm158

[email protected]

Tue 9/19/2017 4:17 PM

To:

[email protected];

Here is the exam review for our next major lecture exam which will be on Monday. Notice that there are a few things missing, such as endochondral ossification. These will be added so just because it does not show up on this exam review doesn't mean you shouldn't study it. That being said, the details of each and every bone which I've gone over in lecture will be on the lab practical rather than the written lecture exam.

Anat 1, Exam 2. Spr 2016 LASC Name:____________________________________________________

1) A synarthrosis: a) is filled with synovial fluid. b) allow for a wide range of movement. c) includes the squamosal suture. d) is exemplified by the shoulder. e) all of the above.

2) Bursae: a) are located in the right atrium. b) are like elastomeric shock absorbers. c) are found in skeletal muscle fibers. d) form the sarcoplasmic reticulum. e) none of the above.

3) Irregular bones: a) can act like cams. b) can provide sites for muscle attachment. c) can protect soft-tissue organs. d) can act as levers. e) all of the above.

4) Condyles: a) are smooth articular surfaces. b) allow blood vessels to enter the bones. c) occur beneath the nail body after an injury. d) are produced by infected sebaceous glands. e) none of the above.

5) A head: a) is where you will find hyaline cartilage. b) is a smooth articular surface. c) is where a bone meshes with another bone. d) all of the above. e) none of the above.

6) Which of the following is the proper sequence of things following a bone fracture: a) hematoma, fibrous callus, bony callus, remodeling. b) hematoma, bony callus, fibrous callus, remodeling. c) hematoma, remodeling, fibrous callus, bony callus. d) hematoma, remodeling, bony callus, fibrous callus. e) fibrous callus, bony callus, remodeling, hematoma.

7) A diaphysis: a) contains yellow bone marrow. b) contain a lot of spongy bone tissue. c) occurs at the ends of long bones. d) all of the above. e) none of the above.

8) Short bones: a) protect underlying soft tissue organs. b) include the ribs. c) include the cranial bones of the skull. d) transfer mechanical forces. e) all of the above.

9) Fibrous joints: a) contain cruciate ligaments. b) include the pubic symphysis. c) are typically found in third class levering systems. d) include the lambdoid suture. e) all of the above.

10) Which of the following doesnât belong? a) tibiofibular joint. b) dentino-alveolar joint.
c) intervertebral disc. d) radioulnar articulation. e) cartilage.

11) Which of the following doesnât belong? a) atlanto-occipital joint. b) humero-ulnar joint. c) frontal suture d) acromio-humeral joint. e) tibiotarsal joint.

12) Hyaluronic acid: a) forms the extracellular matrix. b) is found in fibrous joints. c) keeps cartilage soft and pliable. d) is found in synostoses. e) none of the above.

13) First class levers: a) include the tibio-tarsal joint. b) have the effort between the fulcrum and the load. c) are like a teeter-totter. d) all of the above. e) none of the above.

14) Synchondroses: a) are typically synovial joints. b) allow for very limited movement. c) include sutures and gomphoses. d) are encased in synovial capsules. e) none of the above.

15) Parallel muscles: a) have long excursions. b) include the abdominal muscles. c) have excellent endurance. d) have low strength. e) all of the above.

16) Sphincteral muscles: a) enclose openings or passageways. b) are used when you talk.
c) surround the eyes. d) include the orbicularis oculi. e) all of the above.

17) Pennate muscle architecture: a) is typified by the pectoralis major. b) have high endurance.
c) generates high strength. d) has a longer excursion. e) all of the above

18) Endomysium: a) consists of dense fibrous connective tissue. b) surrounds each fasciculus.
c) surrounds bundles of muscle cells. d) all of the above. e) none of the above.

19) Cartilage: a) heals quickly if it is damaged. b) forms the lining of blood vessels. c) is found on the articular surfaces of bones. d) is a type of epithelial tissue. e) none of the above.

20) A tuberosity: a) is a hollow opening. b) is a shallow smooth articular surface. c) is a raised area that adjoins a condyle. d) is a larger outwardly curved articular surface. e) is a raised, rough-textured area.

21) Which of these doesnât belong? a) tuberosity b) trochanter c) condyle d) tubercle e) lunula

22) Epimysium: a) wraps around the entire muscle. b) is made of dense fibrous connective tissue. c) is continuous with tendons. d) all of the above. e) none of the above.

23) Which of the following is more likely to be an insertion rather than an origin? a) ulna.
b) cervical vertebra. c) thoracic vertebra. d) rib. e) Ischium.

24) Which of the following is more likely to be an origin rather than an insertion? a) clavicle.
b) tibia. c) radius. d) ulna. e) metatarsal.

25) Myofibrils: a) are composed of many muscle fibers. b) are composed of many muscle cells.
c) are composed of many sarcomeres. d) form the endomysium. e) all of the above.

26) Myosin: a) helps keep muscle cells from overstretching. b) is a protein. c) joins thin filaments together. d) forms part of the z-disc. e) all of the above.

27) Sarcolemma: a) surrounds the entire muscle organ. b) surrounds the endomysium.
c) is the cell membrane of a muscle fiber. d) surrounds the epimysium. e) none of the above.

28) Thin filaments: a) are made of titin. b) are pulled on by the thick filaments during contraction.
c) create the molecular âpower-strokeâ. d) all of the above. e) none of the above.

29) A second class lever: a) is like a wheel barrow. b) is like a teeter-totter. c) describes the humeroulnar joint. d) describes the atlanto-occipital joint. e) none of the above.

30) A sarcomere: a) is the basic unit of muscle function. b) is made mostly of proteins. c) shortens during a contraction. d) delivers an âall or noneâ response. e) all of the above.

31) Fast glycolytic fibers: a) have excellent endurance. b) deliver lots of power.
c) are more reddish in color than oxidative fibers. d) none of the above. e) all of the above.

32) Which of the following doesnât belong? a) Vastus lateralus. b) Vastus intermedius. c) Vastus medialis. d) Rectus Femoris. e) Gluteus minimus.

33) Which of the following doesnât belong? a) Teres major. b) Teres minor. c) subscapularis.
d) infraspinatus. e) supraspinatus.

34) Tendon sheaths: a) are filled with synovial fluid. b) can be likened to brake and shifter cable sheathing on a bike. c) are found around the carpal bones. d) really make life unpleasant if they get inflamed. e) all of the above.

35) Epithelial tissues: a) function in movement. b) conduct electrical impulses. c) form a structure for attachment of other organs. d) form barriers and walls. e) all of the above.

36) Elastic connective tissue: a) is found in bone. b) lines the inside of the trachea. c)Is found in small blood vessels like capillaries. d) is found in large arteries. e) all of the above.

37) Cartilage: a) heals quickly if it is damaged. b) forms the lining of blood vessels. c) is found on the articular surfaces of bones. d) is a type of epithelial tissue. e) none of the above.

38) Dense regular connective tissue: a) is poorly vascularized. b) heals slowly if at all. c) forms tendons and ligaments. d) can look a lot like smooth muscle under the microscope. e) all of the above.

39) Transitional epithelium: a) lines the urinary bladder. b) lines the blood vessels. c) contains cilia. d) joins the epidermis to the dermis. e) none of the above.

40) Skeletal muscle: a) responds to conscious thought. b) is found in the heart. c) is found in the walls of blood vessels and the GI tract. d) is composed of very small cells. e) all of the above.

For the following matching questions, each choice is used only once.

41) Fibroblast a) maintains bone tissue
42) Mast Cell b) secretes mucus
43) Chondrocyte c) responsible for inflammation response
44) Osteocyte d) makes collagen fibers
45) Goblet Cell e) maintains cartilage

For the following true-false questions, mark âAâ for true and âBâ for false.

46) Simple cuboidal epithelium is lines the trachea and Fallopian tubes/oviducts.
47) Elastic cartilage joins the ribs to the sternum.
48) An insertion is the more movable point of muscle attachment.
49) Tendons connect muscle to muscle or bone to bone.
50) Ligaments connect muscle to bone.
51) Transverse tubules allow nutrients to be dispersed throughout very large muscle cells.
52) Muscle twitch occurs when only a few muscle cells in the entire muscle are fully contracted.
53) Slow oxidative fibers have poor strength but excellent endurance.
54) Muscles can lengthen under their own power as well as contract.
55) Pottâs fracture is typical of skateboarders.
56) An incomplete fracture is a complete break through the entire bone.
57) Tetanus is the recruitment of additional fibers during muscle contraction.
58) Menisci are like elastomeric shock absorbers.
59) Diarthrotic joints allow for little to no movement.
60) A belly is the contractile portion of a muscle.
61) Synergistic muscles work with each other.
62) Muscle tissue, like your lab instructorâs evil twin before his morning coffee, is irritable.

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LQB185 Lecture Notes - Lecture 10: Dense Irregular Connective Tissue, Bone Marrow, Hyaline Cartilage

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