MFAC1521 Lecture Notes - Lecture 6: Cumulus Oophorus, Folliculogenesis, Corpus Albicans
12 Jul 2018
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Oocyte production: the number of eggs throughout a woman"s life. 2 million primordial follicles (cells = primary oocyte arrested at prophase i) 500,000 primordial follicles (primary oocyte completes meiosis i, arrested in metaphase. *10 days (during late luteal and early follicular phase) Outcomes: many fsh-stimulated follicles (specifically their granulosa cells) are producing a lot of estrogen which eventually causes a surge in estrogen >200pg/ml changes negative feedback of estrogen to positive feedback on hypothalamus promotes. *selection of one mature follicle happens when a follicle has enough fsh receptors that a fall in fsh production by inhibin b does not affect its estrogen production. Selection of follicle (late follicular phase, 2 days before ovulation) Outcomes: pre-ovulatory surge in fsh and lh that leads to ovulation. Lutein cells of the corpus luteum (mid-luteal phase) The rupture follicle remaining in the ovary turns into the corpus luteum. The granulosa cells differentiate granulosa lutein cells of the cl.
