MEDI7212 Lecture Notes - Lecture 23: Glycoprotein, Cotransporter, Hypotension
Document Summary
Fluid/ electrolyte physiology: terminology, diffusion - a process whereby solute particles fill available solvent volume driven by concentration gradients, possibly also electrical gradients. Intracellular = fluid inside cell: osmosis - water diffusion across semi-permeable membrane, extracellular = fluid outside cell but in interstitial space & intravascular fluid, osmolarity (kg, osmolality (l) Interstitial = fluid between cells in interspaces of a tissue. Fluid composition: 60% total body weight is total body fluid/ water, exception - neonate (80% fluid), elderly (50% fluid), obese (less fluid bc adipose tissue doesn"t contain fluid, 60ml/ kg body weight is blood volume. 2/3 is intracellular: barrier is cell membrane. Inside plasma membrane of body cells/ blood cells/ other cells. Input: 500ml = ingested water, 800ml = water content in food, 300ml = water from oxidation, total = 1600ml. Pathological loss of h2o: 500ml = urine, 200ml = stool, 500ml = skin, 400ml = respiratory tract, total = 1600ml.
