MEDI7212 Lecture Notes - Lecture 71: Intensive Care Unit, Anticholinergic, Anatomical Terms Of Motion
Document Summary
Introduction coma is an unarousable unresponsive state that can be produced by a number of acute or subacute cns insults, thus causing absent voluntary movement or behaviour in the presence of verbal and tactile stimuli (eg pain) Lethargy, obtundation and stupor are terms to denote mild, moderate and severe disturbances in responsiveness/ consciousness respectively: poorly quantifiable and unvalidated in terms of reliability, thus best to acoid these terms. & its bilateral projections to thalamus and cerebral hemispheres: coma involves dysfunction of either bilateral cerebral hemispheric functioning and/or bras. Following coma, patient may deteriorate (progressive neuronal damage -> brain death) or show evidence of recovery via progression to vegetative state, minimally conscious state or other related clinical syndromes. Similar pathophysiology to syncope except you don"t wake up: causes (acute coma) bold = more common, italics = rare. Intracerebral hemorrhage (first differential for elderly), subdural hematoma, epidural hematoma, cerebral contusion, brain abscess, cerebral infarction, brain tumour, head trauma.
